78% of reviewers reported a positive experience, while 13% reported a negative experience. Descriptions Sildenafil is used to treat men who have erectile dysfunction (also called sexual impotence). Patients receiving indinavir with ritonavir should receive not more than 25 mg of sildenafil for treatment of erectile dysfunction in a 48-hour period, and patients receiving other protease inhibitors should use a lower initial sildenafil dose of 25 mg. Use Caution/Monitor. Do not use more of it and do not use it more often than your doctor ordered. When you're ready to get to "business," you take sildenafil, which in an appropriate dosage will prepare you for better action for the next few hours, according to the National Library of Medicine. Slowly pull back the plunger until the required dose. Use Caution/Monitor. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. Avoid or Use Alternate Drug. enzalutamide will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The penis is one of the areas where this enzyme works. Monitor Closely (1)letermovir increases levels of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Sildenafil under the name Viagra is used to treat erectile dysfunction (impotence) in men. Contraindicated. Use Caution/Monitor. This is a type of high blood pressure that occurs between the heart and the lungs. Serious - Use Alternative (1)levoketoconazole will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Mechanism: additive vasodilation. The following information includes only the average doses of this medicine. This medicine can cause serious side effects in patients with heart problems. 1, 6 The dose can be increased . When used for erectile dysfunction, consider reducing initial sildenafil dose of 25 mg in patients also taking a strong CYP3A4 inhibitor and monitor for sildenafil toxicities (eg, dyspepsia, headache, hypotension). Use Caution/Monitor. sildenafil, riociguat. This drug is available at a higher level co-pay. Use of nitroglycerin within a few days of PDE5 inhibitors is contraindicated. Use Caution/Monitor. Avoid or Use Alternate Drug. Serious - Use Alternative (1)crizotinib increases levels of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Sildenafil 20 mg is a dosage approved to treat a lung condition called pulmonary arterial hypertension (PAH), but it's also prescribed to treat erectile dysfunction (ED). butabarbital will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)acebutolol increases effects of sildenafil by additive vasodilation. Call your doctor for medical advice about side effects. Use Caution/Monitor. sotalol increases effects of sildenafil by additive vasodilation. Filter by condition Sildenafil rating summary 8.2/10 average rating 392 ratings from 431 user reviews. anastrozole will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. A: Generally acceptable. Monitor CYP3A4 substrates coadministered with stiripentol for increased or decreased effects. Either increases effects of the other by pharmacodynamic synergism. Does viagra make sex better. Use Caution/Monitor. hydrocortisone will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. voriconazole will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor (1)cyclophosphamide will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. lenacapavir will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)tazemetostat will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If coadministration is unavoidable, monitor patients for loss of therapeutic effect of these drugs. Consider increasing CYP3A substrate dose if needed. Use Caution/Monitor. Adding plans allows you to compare formulary status to other drugs in the same class. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels, Serious - Use Alternative (1)phenobarbital will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Revatio treats pulmonary arterial hypertension. When used chronically for PAH, sildenafil is contraindicated for use with cobicistat; if used for erectile dysfunction, do not exceed sildenafil 25 mg q48hr. Potentially fatal hypotension. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. Pulmonary veno-occlusive disease or PVOD (a type of lung disease)Use with caution. Coadministration contraindicated if sildenafil used for pulmonary arterical hypertension. posaconazole will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Is 20 mg an Effective Dose of Sildenafil? | Ro By clicking send, you acknowledge that you have permission to email the recipient with this information. Monitor Closely (1)epoprostenol increases effects of sildenafil by additive vasodilation. fosphenytoin will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)butalbital will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Monitor Closely (1)griseofulvin will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. After discontinuation of a strong CYP3A inhibitor, resume crizotinib dose used prior to initiating the strong CYP3A4 inhibitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor Closely (1)butabarbital will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This medicine is available only with your doctor's prescription. nifedipine will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Risk of hypotension. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Tell your doctor if your condition does not improve. Monitor Closely (1)sildenafil will increase the level or effect of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Liver disease, severeUse with caution. propranolol increases effects of sildenafil by additive vasodilation. Use Caution/Monitor. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs that are CYP3A4 substrates can result in lower exposure to these medications. sildenafil increases effects of doxazosin by pharmacodynamic synergism. Adult Initially 50 mg, to be taken approximately 1 hour before sexual activity, adjusted according to response to 25-100 mg (max. ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)miconazole vaginal will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor (1)sapropterin, sildenafil. Monitor Closely (1)zafirlukast will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Increased risk of orthostatic hypotension. Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Contraindicated. deferasirox will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Risk of hypotension. Use Caution/Monitor. "We prescribe one 20-mg tablet a night, a classic dose," he said . Use Caution/Monitor. Potentially fatal hypotension. Use Caution/Monitor. If unavoidable, reduce CYP3A substrate dose according to product labeling. This website also contains material copyrighted by 3rd parties. SIDE EFFECTS: Dizziness, headache, flushing, or stomach upset may occur. Patients receiving indinavir with ritonavir should receive not more than 25 mg of sildenafil for treatment of erectile dysfunction in a 48-hour period, and patients receiving other protease inhibitors should use a lower initial sildenafil dose of 25 mg. Mechanism: additive vasodilation. If using Viagra, consider decreasing starting dose. Avoid or Use Alternate Drug. Monitor Closely (1)darunavir will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. sildenafil increases effects of silodosin by pharmacodynamic synergism. Alcohol or marijuana (cannabis) can make you more dizzy. Modify Therapy/Monitor Closely. Either increases effects of the other by pharmacodynamic synergism. If you see air bubbles in the syringe, repeat the steps. Contraindicated (1)nirmatrelvir will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The penis is one of the areas where this enzyme works. These side effects may go away during treatment as your body adjusts to the medicine. Viagra online Genuine Viagra makes it possible about Viagra How to Take Sildenafil With Food Before popping that little blue pill, there are a few things you should know. aprepitant will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Avoid or Use Alternate Drug. nevirapine will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Using alcohol or tobacco with certain medicines may also cause interactions to occur. coq10 for erectile dysfunction and cialis daily vs 36 hour? Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as saquinavir), mifepristone, rifampin, ritonavir, among others.Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil). It works by dilating blood vessels and increasing blood flow to certain areas of the body. Contraindicated. Use Caution/Monitor. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels, pentobarbital will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. commonly, these are "non-preferred" brand drugs or specialty Avoid or Use Alternate Drug. Monitor Closely (1)elagolix decreases levels of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)mifepristone will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. Avoid or Use Alternate Drug. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. Patients receiving indinavir with ritonavir should receive not more than 25 mg of sildenafil for treatment of erectile dysfunction in a 48-hour period, and patients receiving other protease inhibitors should use a lower initial sildenafil dose of 25 mg. Monitor Closely (1)isoniazid will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Enhanced hypotensive effects. Sickle-cell anemia (blood disorder)Sildenafil should be used with caution in these patients as problems with prolonged erection of the penis may occur. commonly, these are "non-preferred" brand drugs. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. Avoid or Use Alternate Drug. Use Caution/Monitor. Coq10 For Erectile Dysfunction ! Sildenafil 20 Mg Reviews Sildenafil does not protect you from STIs. Either increases effects of the other by pharmacodynamic synergism. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Avoid or Use Alternate Drug. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. Avoid or Use Alternate Drug. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. The dose of this medicine will be different for different patients. Assessment of the grade of erectile dysfunction using international index of erectile function-5.The patients whose international Index of Erectile Function-5 (IIEF-5) scores varied between 5-7 are considered to have severe and 8-16 are considered to have moderate and 17-21 are . Contraindicated. Monitor Closely (1)artemether/lumefantrine will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration of encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. lapatinib will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. chloramphenicol will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. PRECAUTIONS: Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Sildenafil: MedlinePlus Drug Information Use Caution/Monitor. Fezolinetant AUC and peak plasma concentration are increased if coadministered with drugs that are weak, moderate, or strong CYP1A2 inhibitors. Mechanism: additive vasodilation. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. affecting hepatic/intestinal enzyme CYP3A4 metabolism. Most Use Caution/Monitor. Avoid or Use Alternate Drug. Sildenafil has an average rating of 8.2 out of 10 from a total of 392 reviews for the treatment of Erectile Dysfunction. Adjust dose according to prescribing information if needed. Information last revised October 2022. 2010revatio-viagra-sildenafil-342834Drugs, You are being redirected to Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. Use Caution/Monitor. Monitor Closely (1)istradefylline will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease, liver disease, high or low blood pressure, dehydration, penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma), eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION).This drug may make you dizzy or cause vision problems. Serious - Use Alternative (1)ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. For instance, Tadalafil (Cialis) can work for a day or more, but sildenafil is best taken as a sort of pre-game erectile dysfunction solution. Sildenafil Dosage Guide + Max Dose, Adjustments - Drugs.com Contraindicated (1)isosorbide dinitrate, sildenafil. 2023 May 1;4(5):631-640. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. Additive hypotensive effects. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. Different brands may not work the same way. Erectile dysfunction: Viagra and other oral medications cenobamate will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. Children 1 year of age and older weighing 45 kilograms (kg) or more20 mg 3 times a day. Coadministration with duvelisib increases AUC of a sensitive CYP3A4 substrate which may increase the risk of toxicities of these drugs. grapefruit will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. nitroglycerin topical, sildenafil. timolol increases effects of sildenafil by additive vasodilation. Use Caution/Monitor. Both drugs lower blood pressure. Mechanism: additive vasodilation. Avoid or Use Alternate Drug. Monitor Closely (1)carbamazepine will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. An atypical erectile dysfunction patient with infertility treated with Rationale: Erectile dysfunction (ED) is common in middle-aged and elderly men, affecting more than 100 million males worldwide. Sildenafil has systemic vasodilatory properties and may further lower blood pressure in patients taking antihypertensive medications. ribociclib will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Erectile dysfunction for sildenafil By mouth. Serious - Use Alternative (1)ceritinib will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. It continues to work for up to 4 hours, although its action is usually less after 2 hours. If unavoidable, reduce CYP3A substrate dose according to product labeling. Use Caution/Monitor. nitroprusside sodium, sildenafil. Since high blood pressure in the lungs is a serious condition that can harm both a pregnant woman and her unborn baby, do not stop this medication unless directed by your doctor. Avoid or Use Alternate Drug. fexinidazole will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)abametapir will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Posted on 2023-06-28 2023-06-28 by ceac-admin. Portions of this document last updated: June 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/sildenafil-oral-route/proper-use/DRG-20066989. Enhanced hypotensive effects. Coadministration with PDE-5 inhibitors may result in an increase in PDE-5 inhibitor-associated adverse reactions (eg, hypotension, syncope, visual disturbances and priapism). Avoid or Use Alternate Drug. If you experience a sudden loss of vision in one or both eyes, contact your doctor immediately. lonafarnib will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Never use combination with chronic sildenafil for PAH, cobicistat will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The 20 mg strength of sildenafil generic is the same as Revatio. Modify Therapy/Monitor Closely. Contraindicated (1)nitroglycerin topical, sildenafil. Consider reducing the dose of the sensitive CYP3A4 substrate and monitor for signs of toxicities of the coadministered sensitive CYP3A substrate. If your dose is different, do not change it unless your doctor tells you to do so. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. Potentially fatal hypotension. Contraindicated. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. The recommended dosage for tablet and oral suspension formularies is 5 mg or 20 mg three times daily, 4 to 6 hours apart. Avoid or Use Alternate Drug. Alternative Treatments. . metoprolol increases effects of sildenafil by additive vasodilation. Use Caution/Monitor. Contraindicated. Contraindicated (1)nirmatrelvir/ritonavir will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. Contraindicated. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels, rifampin will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)glyceryl trinitrate pr, sildenafil. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Use of Sildenafil (Viagra) in Patients With Cardiovascular Disease Avoid or substitute another drug for these medications when possible. saquinavir increases levels of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Mechanism: additive vasodilation. If you take too much sildenafil or take it together with these medicines, the chance for side effects will be higher. Individual plans may vary Serious - Use Alternative (1)oxcarbazepine will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. Potentially fatal hypotension. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Patients receiving indinavir with ritonavir should receive not more than 25 mg of sildenafil for treatment of erectile dysfunction in a 48-hour period, and patients receiving other protease inhibitors should use a lower initial sildenafil dose of 25 mg. Although its place in disease management is still emerging and there are contraindications to its use, i Practice "safe sex" such as using latex condoms. Its effect may last up to 36 hours. Use protective measures and ask your doctor if you have any questions about this. Monitor Closely (1)sotalol increases effects of sildenafil by additive vasodilation. carbamazepine will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Controlled studies in pregnant women show no evidence of fetal risk. Monitor Closely (1)hydrocortisone will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid concurrent or sequential use to decrease risk for ototoxicity. griseofulvin will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. duvelisib will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Reduce sildenafil dose if used for erectile dysfunction. Coadministration with strong CYP3A4 inhibitors and sildenafil (for pulmonary arterial hypertension) is not recommended. Some illegal ("street") drugs called "poppers" (such as amyl nitrate, butyl nitrate, or nitrite). Minor/Significance Unknown. Use Caution/Monitor. Avoid or Use Alternate Drug. The body takes longer to absorb it after a high-fat meal or alcohol. Sildenafil User Reviews for Erectile Dysfunction - Drugs.com Stronger Erectile. This effect was not observed with istradefylline 20 mg/day. Your doctor may adjust your dose as needed and tolerated. Contraindicated (1)sildenafil will increase the level or effect of fezolinetant by affecting hepatic enzyme CYP1A2 metabolism. Avoid or Use Alternate Drug. Copyright(c) 2023 First Databank, Inc. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. To date, the Company has identified men's wellness telemedicine services and products as a growing sector and especially related to the area of erectile dysfunction (ED). nebivolol increases effects of sildenafil by additive vasodilation. Use Caution/Monitor. If used concomitantly, monitor for toxicities. Your doctor may adjust your dose if needed. You may report side effects to the FDA at 1-800-FDA-1088. tobramycin inhaled and sildenafil both increase nephrotoxicity and/or ototoxicity. Cobicistat is a CYP3A4 inhibitor; contraindicated with CYP3A4 substrates for which elevated plasma concentrations are associated with serious and/or life-threatening events; contraindication applies to chronic administration of sildenafil for PAH; for ED, not to exceed 25 mg in 48 hr. Monitor Closely (1)fedratinib will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Remove the cap by pushing it down and twisting it counter-clockwise. carvedilol increases effects of sildenafil by additive vasodilation. lesinurad decreases levels of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Istradefylline 40 mg/day increased peak levels and AUC of CYP3A4 substrates in clinical trials. Use Caution/Monitor. Use Caution/Monitor. Contraindicated. Comparing The Effect of Tadalafil 5 mg/Day to Sildenafil 25 mg/Day on . Use Caution/Monitor. elagolix decreases levels of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Aim: To assess the efficacy and safety of sildenafil vs placebo according to age subgroups (<65, 65-74, and 75 years) in 11,364 men with erectile dysfunction using pooled data from 48 randomized, double-blinded . If you have any questions, ask your doctor or pharmacist.To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. sildenafil, comes in 20-mg tablets. Use Caution/Monitor. 20-mg sildenafil pill is $4. Avoid or Use Alternate Drug. Although not all of these side effects may occur, if they do occur they may need medical attention. Contraindicated (1)cobicistat will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. butalbital will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. To view formulary information first create a list of plans. Monitor blood pressure. Jiang Shulan smiled mischievously . Roman Review 2023: ED, Hair Loss, and More - Medical News Today cyclosporine will increase the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)bisoprolol increases effects of sildenafil by additive vasodilation. Potentially fatal hypotension. Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. Consider dose reduction of sensitive CYP3A4 substrates. Sildenafil Article - StatPearls lorlatinib will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Monitor blood pressure response to sildenafil in patients receiving concurrent blood pressure lowering therapy. It is important that you tell all of your doctors that you take sildenafil. Risk of hypotension; separate sildenafil >25mg from alpha blocker by 4hr. sildenafil increases effects of phenoxybenzamine by pharmacodynamic synergism. Patient taking sildenafil for PAH with ritonavir is not recommended. Minor/Significance Unknown. Fezolinetant AUC and peak plasma concentration are increased if coadministered with drugs that are weak, moderate, or strong CYP1A2 inhibitors. Tadalafil (Cialis) for Erectile Dysfunction | AAFP Potent CYP3A4 inducers are expected to cause substantial decreases in sildenafil plasma levels. Manufacturer advises reduce dose to 20 mg twice daily with concurrent use of . Use Caution/Monitor. How to Take Sildenafil for Erectile Dysfunction | hims Avoid or Use Alternate Drug. St John's Wort will decrease the level or effect of sildenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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sildenafil 20 mg for erectile dysfunction